Chris Van Hoof received a PhD in Electrical Engineering from the University of Leuven in collaboration with imec in 1992. At imec, he became successively head of the detector systems group (in 1998), director of the microsystems department (in 2002) and Integrated Systems Department (in 2004), and program director (in 2007).

Since 2009 he is department director and program director of HUMAN++ in the smart systems unit at imec in Leuven and the HOLST Centre in Eindhoven.

Integrated microsystems research focuses on the application of advanced technology for the creation of miniature components and subsystems, ultra-low power wearable wireless sensor systems, and smart implantable devices.

Since 2000 Chris Van Hoof is also a guest professor at the University of Leuven.